Update in Transfusion Therapy for Hematologic Malignancies: Transfusion Support – TACO and TRALI
Transfusion therapy for patients with hematological malignancies represents a unique set of circumstances and challenges. Collaboration between transfusion medicine specialists and hematologists is critical to the best patient outcome. The speakers in this session will further our understanding of opportunities to improve transfusion therapy for our patients from transfusion triggers through most appropriate product selection to managing transfusion complications.
Dr. Christine Cserti-Gazdewich will focus her presentation on inconsistencies and gaps in care as they relate to the two-dimensional theme of quantity and quality of our blood ordering, particularly as it relates to red blood cells. She will address blood compatibility testing, matching logistics in hematological malignancies and the most common hazards and impacts that are cumulatively peculiar to hematological malignancies.
Dr. Nadine Shehata will discuss managing patients who are refractory to platelet transfusions. She will address platelet refractoriness, its causes and clinical significance. Dr. Shehata will also present non-immune mediated platelet refractoriness. Finally, she will provide clinically relevant information and suggest approaches to caring for patients with platelet refractoriness. The practicing hematologist will find this presentation highly relevant to daily challenges.
Dr. Nareg Roubinian will discuss pathophysiology of transfusion associated circulatory overload (TACO) and transfusion related acute lung injury (TRALI) based on recent data from in vivo models and clinical investigations. He will present transfusion and recipient risk factors for TACO and TRALI with an emphasis on patients with hematological malignancies. Dr. Roubinian will update the audience on contemporary incidence and prevention of these transfusion complications.
Christine Cserti-Gazdewich, BSc, MD, FRCPC
Nadine Shehata, MD,FRCPC,MSc
Nareg Roubinian, MD
Active, International, Emeritus, and Honorary Members
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